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. Author manuscript; available in PMC: 2020 Jul 19.
Published in final edited form as: Annu Rev Anal Chem (Palo Alto Calif). 2019 Apr 2;12(1):41–67. doi: 10.1146/annurev-anchem-061318-115529

Table 2.

List of NAAT platforms with genotypic resistance detection that are approved by the US Food and Drug Administration (FDA). Adapted from Bard & Lee (53) with permission from Elsevier

Assay Company Specimen type Method Resistance gene Run time
Xpert MRSA/SA Gen 3 Cepheid Blood culture RT-PCR Methicillin (mecA, mecC) ~1 h
Xpert MTB/RIF Cepheid Sputum RT-PCR rpoB (Mycobacterium tuberculosis) < 2 h
Xpert MRSA/SA SSTI Cepheid Swab RT-PCR mecA (Staphylococcus aureus) ~1 h
BD Max StaphSR Becton Dickinson Blood culture RT-PCR mecA (Staphylococcus aureus) ~1.5 h
Verigene Gram-Positive Blood Culture Luminex Blood culture Microarray mecA (Staphylococcus aureus)
vanA, vanB (Enterococcus spp.)		 2.5 h
Verigene Gram-Negative Blood Culture Luminex Blood culture Microarray CTX-M, IMI, VIM, KPC, NDM, OXA (Enterobacteriaceae) 2.5 h
FilmArray Blood Culture identification BioFire Diagnostics Blood culture Nested PCR mecA (Staphylococcus aureus)
vanA, vanB (Enterococcus spp.)
KPC (Enterobacteriaceae)		 1 h

Abbreviations: NAAT, nucleic acid amplification technology; PCR, polymerase chain reaction.