Table 3.
AT(N) profile | AD | MCI | FTD | LBD and PD | VaD and stroke | Indeterminate | No diagnosis | Total |
A-T-(N)- | 6 | 8 | 8 | 6 | 4 | 21 | 10 | 63 |
A+T-(N)- | 11 | 2 | 6 | 1 | 4 | 9 | 2 | 35 |
A+T+(N)- | 4 | 1 | 1 | 1 | 0 | 0 | 1 | 8 |
A+T+(N)+ | 22 | 0 | 2 | 2 | 0 | 4 | 0 | 30 |
A+T-(N)+ | 5 | 0 | 1 | 0 | 0 | 1 | 0 | 7 |
A-T+(N)- | 0 | 0 | 0 | 0 | 0 | 3 | 2 | 5 |
A-T-(N)+ | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A-T+(N)+ | 5 | 1 | 1 | 0 | 1 | 2 | 0 | 10 |
Total | 54 | 12 | 19 | 10 | 9 | 41 | 16 | 161 |
There was a statistically significant difference between all groups (χ2 = 71.22, p = 0.003). AD, Alzheimer’s disease or Alzheimer’s disease atypical variant; MCI, mild cognitive impairment; FTD, frontotemporal dementia; LBD and PD, Lewy’s body dementia and Parkinson’s disease combined; VaD and stroke, vascular dementia and stroke combined; Indeterminate, indeterminate condition; No diagnosis, no neurodegenerative disease; A, biomarker of Aβ plaques (labeled “A”) is low CSF Aβ42; T, biomarker of fibrillary tau (labeled “T”) is elevated CSF phosphorylated tau (P-tau); [N], biomarker of neurodegeneration or neuronal injury [labeled (“N”)] is CSF T-tau.