Fig.4.

Associations of DHA containing lipid species with gender in control and Alzheimer’s disease groups. A) Linear regression of lipid species against gender, adjusting for clinical covariates, omega-3 supplementation and statin use using most recent samples of cognitively normal controls (n = 696). B) Concentrations of total PE(O) and PE(P) species esterified with a 22:6 fatty acid in cognitively normal males (n = 288) and females (n = 408), and in AD males (n = 109) and females (n = 159). p-values were obtained from a Dunn’s test after Kruskal-Wallis analysis. Black lines represent the median with 95% confidence intervals. C, D) Linear regression adjusting for clinical covariates using most recent samples of AD individuals (n = 268). C) No adjustment for omega-3 supplementation. D) Adjusted for omega-3 supplementation.