TABLE I.
Histological Scoring Table
Group | Collagen fiber structure | Collagen fiber arrangement | Rounding of nuclei | Cell population | Chronic inflammation | Total |
---|---|---|---|---|---|---|
DR | 0.0 | 0.0 | 3.0 ± 0.0 | 1.3 ± 0.4 | 0.0 | 4.3 ± 0.4 |
ELAC | 1.8 ± 0.2 | 1.6 ± 0.1 | 1.1 ± 0.1 | 1.7 ± 0.2 | 0.4 ± 0.2 | 6.6 ± 0.6 |
ELAC + MSCs | 1.7 ± 0.1 | 1.2 ± 0.1 | 0.0 | 2.7 ± 0.1 | 0.0 | 5.5 ± 0.3 |
Native tendon parameters were defined as follows: collagen fiber structure: compact and wavy collagen fibers arranged in parallel; collagen fiber arrangement: uniaxial, an angle of less than 20° between fibers; rounding of nuclei: over 95% of nuclei predominately elongated; cell population: sparse, less than 5% coverage of the total visible area: chronic inflammation: no inflammatory cell infiltrates.
Scoring for each parameter reported as mean and standard deviation of each group. Scores were given on a scale from 0 to 3; 0 = characteristic nearly indistinguishable from native tendon, 1 = minimal difference from native tendon, 2 = moderate difference, and 3 = extensive difference. “Total” is the sum of the scoring parameters (15 = no visible characteristics of native tendon and 0 = nearly indistinguishable from native tendon).