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. Author manuscript; available in PMC: 2020 Jul 19.
Published in final edited form as: J Biomed Mater Res B Appl Biomater. 2018 Nov 28;107(6):1864–1876. doi: 10.1002/jbm.b.34279

TABLE I.

Histological Scoring Table

Group Collagen fiber structure Collagen fiber arrangement Rounding of nuclei Cell population Chronic inflammation Total
DR 0.0 0.0 3.0 ± 0.0 1.3 ± 0.4 0.0 4.3 ± 0.4
ELAC 1.8 ± 0.2 1.6 ± 0.1 1.1 ± 0.1 1.7 ± 0.2 0.4 ± 0.2 6.6 ± 0.6
ELAC + MSCs 1.7 ± 0.1 1.2 ± 0.1 0.0 2.7 ± 0.1 0.0 5.5 ± 0.3

Native tendon parameters were defined as follows: collagen fiber structure: compact and wavy collagen fibers arranged in parallel; collagen fiber arrangement: uniaxial, an angle of less than 20° between fibers; rounding of nuclei: over 95% of nuclei predominately elongated; cell population: sparse, less than 5% coverage of the total visible area: chronic inflammation: no inflammatory cell infiltrates.

Scoring for each parameter reported as mean and standard deviation of each group. Scores were given on a scale from 0 to 3; 0 = characteristic nearly indistinguishable from native tendon, 1 = minimal difference from native tendon, 2 = moderate difference, and 3 = extensive difference. “Total” is the sum of the scoring parameters (15 = no visible characteristics of native tendon and 0 = nearly indistinguishable from native tendon).