TABLE II.
Qualitative IHC Assessment
Scaffold alone |
Cell-seeded scaffold |
|||||
---|---|---|---|---|---|---|
Direct repair | Inside | Outside | Inside | Outside | Native tendon | |
Collagen I | 2/3 | 3/3 | 3/3 | 3/3 | 3/3 | 2/2 |
Collagen III | 3/3 | 3/3 | 3/3 | 3/3 | 3/3 | 0/2 |
Tenomodulin | 0/3 | 2/3 | 3/3 | 1/3 | 3/3 | 2/2 |
Procollagen I | 0/3 | 3/3 | 2/3 | 3/3 | 2/3 | 0/2 |
Slides from three specimens in each of the experimental groups were assessed in a binary fashion (positive = 1, negative = 0). “Inside” refers to tissue and cells within the continuum of the scaffold structure and “outside” is in reference to the fibrous tissue immediately beyond the continuum of the scaffolds.