6. Clinical response rate assessed by RECIST v1.0 by cancer type in patients treated with fluzoparib.
Variables | Ovarian cancer | Breast cancer | Colorectal cancer | Gastric cancer and other tumor types | Total |
RECIST, Response Evaluation Criteria in Solid Tumor; CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease; ORR, objective response rate; DCR, disease control rate. | |||||
Total subjects | 47 | 16 | 8 | 8 | 79 |
Efficacy evaluable subjects | 37 | 13 | 8 | 7 | 65 |
CR | 0 | 0 | 0 | 0 | 0 |
PR | 3 | 1 | 0 | 0 | 4 |
SD | 14 | 2 | 0 | 0 | 16 |
PD | 20 | 10 | 8 | 7 | 45 |
ORR based on total subjects (%) | 6.4 | 6.3 | 0 | 0 | 5.1 |
DCR based on total subjects (%) | 36.2 | 18.8 | 0 | 0 | 25.3 |
ORR based on evaluable subjects (%) | 8.1 | 7.7 | 0 | 0 | 6.2 |
DCR based on evaluable subjects (%) | 45.9 | 23.1 | 0 | 0 | 30.8 |