1. Four molecular subtypes of GC/GEJC proposed by the Cancer Genome Atlas Research Network. Each portion of the pie chart lists defect or mutated genes involved in certain subtype. PD-L1 expression level and tumor immunogenicity are also labeled. GC, gastric cancer; GEJC, gastroesophageal junction cancer; PD-L1, programmed cell death 1 ligand; EBV, Epstein-Barr virus; MSI, microsatellite instability; GS, genome stable; CIN, chromosomal instability.
