Table 1. Predominant Clinical Findings of Patients with COVID-19.
| Characteristics | Training Cohort (n = 166) | Validation Cohort (n = 72) | P |
|---|---|---|---|
| Age (years) | 43.8 ± 12.3 | 45.1 ± 15.8 | 0.567 |
| Sex (male/female ratio) | 103/63 | 38/34 | 0.233 |
| Duration (days) | 3 (0–8) | 4 (0–7) | 0.306 |
| Epidemiological history (%) | 0.203 | ||
| Direct exposure history | 86 (51.8) | 29 (40.3) | |
| Indirect exposure history | 47 (23.3) | 28 (38.9) | |
| No exposure history | 33 (19.9) | 15 (20.8) | |
| Symptoms (%) | 0.871 | ||
| Fever | 132 (79.5) | 50 (69.4) | |
| Cough | 86 (51.8) | 31 (43.1) | |
| Fatigue | 24 (14.5) | 9 (12.5) | |
| Chest distress | 19 (11.5) | 7 (9.7) | |
| Diarrhea | 5 (3.0) | 3 (4.2) | |
| Headache | 7 (4.2) | 2 (2.8) | |
| None | 5 (3.0) | 3 (4.2) | |
| Underlying comorbidity (%) | 0.565 | ||
| Endocrine system disease | 20 (12.0) | 10 (13.9) | |
| Cardiovascular and cerebrovascular disease | 15 (9.0) | 6 (8.3) | |
| Digestive system disease | 12 (7.2) | 5 (6.9) | |
| Malignancy | 4 (2.4) | 2 (2.8) | |
| Mental disease | 1 (0.6) | 1 (1.4) | |
| Urinary system disease | 7 (4.2) | 3 (4.2) | |
| Respiratory system disease | 2 (1.2) | 0 (0.0) | |
| None | 112 (67.5) | 52 (72.2) | |
| White blood cell count (x 109/L) | 5.11 (1.99–10.17) | 5.72 (2.60–14.24) | 0.081 |
| Lymphocyte count (x 109/L) | 1.10 (0.43–2.15) | 1.34 (0.41–2.81) | < 0.001* |
| C-reactive protein (mg/L) | 12.80 (0.49–198.10) | 9.80 (0.35–156.90) | 0.191 |
| Procalcitonin (ng/mL) | 0.04 (0.00–0.91) | 0.03 (0.01–0.94) | 0.499 |
| Alanine aminotransferase (U/L) | 24.50 (6.00–363.90) | 23.00 (6.00–267.00) | 0.339 |
| Aspartate aminotransferase (U/L) | 27.00 (9.60–208.20) | 25.00 (8.20–218.00) | 0.106 |
| Therapeutic strategy (%) | 0.424 | ||
| Antiviral therapy | 149 (89.7) | 64 (88.9) | |
| Antibiotic treatment | 102 (61.5) | 35 (56.9) | |
| Oxygen inhalation | 52 (31.3) | 21 (29.2) | |
| Interferon therapy | 18 (10.8) | 8 (11.1) | |
| Glucocorticoid therapy | 16 (9.6) | 3 (4.2) |
*p < 0.050. COVID-19 = coronavirus disease