Figure 7. Roles of CD44 and Ezrin/Radixin/Moesin Phosphorylation in the Phagocytosis of Bacteria by LPS-Stimulated RAW 264.7 Cells.
(A) The effect of blocking CD44 on HMW HA-induced enhancement of bacterial elimination in the supernatant of LPS-stimulated RAW264.7 cells (N=14 in each group). (B, C) The effects of HA and CD44 blocking antibodies on the profiles of inflammatory cytokines in LPS-stimulated RAW264.7 cells (N=8 in each group). (D, E) The effect of HA on phosphorylated ERM in LPS-stimulated RAW264.7 cells (N=9 in each group). (F) The effect of ezrin inhibition on HA-induced enhancement of bacterial elimination in the supernatant of LPS-stimulated RAW264.7 cells (N=20 in each group). *P<0.05, **P<0.01.