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. 2020 Jun;10(3):453–469. doi: 10.21037/cdt-20-129

Figure 5.

Figure 5

PQQ reduced mitochondrial biogenesis dysfunction caused by pressure overload both in vivo and in vitro. (A) Western blot analyses of PGC-1α and TFAM in the sham, TAC, and TAC + PQQ groups. (B,C) Quantification of the PGC-1α and TFAM protein levels in rat LV tissue. The data are expressed as the mean ± SD. **P<0.01 vs. sham. ##P<0.01 vs. TAC; (D) Western blot analyses of PGC-1α and TFAM in the control, Ang II, and Ang II + PQQ groups. (E,F) Quantification of the PGC-1α and TFAM protein levels in NRVMs. The data are expressed as the mean ± SD. **P<0.01 vs. control. ##P<0.01 vs. Ang II.