Table 2. Allelic association analysis between the variants in HMGB1 and AF in the Chinese Han population.
| SNP-allele (N, case/control) | Frequency | Phwb | Pobs | Padj | OR (95% CI) | |
|---|---|---|---|---|---|---|
| Case | Control | |||||
| Rs1045411T/C (1,152/1,738) | 0.203/0.797 | 0.194/0.806 | 0.705 | 0.520 | 0.839 | 1.03 (0.77–1.38) |
| Rs1412125C/T (1,152/1,738) | 0.271/0.729 | 0.272/0.728 | 0.595 | 0.982 | 0.715 | 0.95 (0.73–1.24) |
SNP, single nucleotide polymorphism; AF, atrial fibrillation; MAF, minor allele frequency; Pobs, observed P value; Phwe, P value of the Hardy-Weinberg equilibrium tests; Padj, P value after adjusting for age, gender, hypertension, diabetes mellitus and smoking history; OR, odds ratio after the adjustment.