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. 2020 Jun;10(3):388–395. doi: 10.21037/cdt.2019.12.07

Table 2. Allelic association analysis between the variants in HMGB1 and AF in the Chinese Han population.

SNP-allele (N, case/control) Frequency Phwb Pobs Padj OR (95% CI)
Case Control
Rs1045411T/C (1,152/1,738) 0.203/0.797 0.194/0.806 0.705 0.520 0.839 1.03 (0.77–1.38)
Rs1412125C/T (1,152/1,738) 0.271/0.729 0.272/0.728 0.595 0.982 0.715 0.95 (0.73–1.24)

SNP, single nucleotide polymorphism; AF, atrial fibrillation; MAF, minor allele frequency; Pobs, observed P value; Phwe, P value of the Hardy-Weinberg equilibrium tests; Padj, P value after adjusting for age, gender, hypertension, diabetes mellitus and smoking history; OR, odds ratio after the adjustment.