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| Gene | Haplotype | Male | Female | |||
|---|---|---|---|---|---|---|
| Padj | OR (95% CI) | Padj | OR (95% CI) | |||
| HMGB1 (rs1045411T/C-rs1412125C/T) | T-C | 0.615 | 1.23 (0.54–2.80) | 0.446 | 1.41 (0.58–3.40) | |
| T-T | 0.265 | 1.31 (0.82–2.11) | 0.097* | 0.67 (0.42–1.07) | ||
| C-C | 0.538 | 1.14 (0.75–1.73) | 0.086* | 0.71 (0.48–1.05) | ||
| C-T | – | – | – | – | ||
*, P<0.1. Pobs, observed P value; Padj, P value adjusted for age, hypertension, diabetes mellitus and smoking history; OR, odds ratio after the adjustment.
