Table S2. Haplotypic association analysis of HMGB1 with AF in the onset age subgroups.
| Gene | Haplotype | Early onset | Lately onset | |||
|---|---|---|---|---|---|---|
| Padj | OR (95% CI) | Padj | OR (95% CI) | |||
| HMGB1 (rs1045411T/C-rs1412125C/T) | T-C | 0.519 | 1.22 (0.67–2.20) | 0.138 | 2.79 (0.72–10.8) | |
| T-T | 0.691 | 0.93 (0.67–1.31) | 0.646 | 0.85 (0.41–1.73) | ||
| C-C | 0.511 | 0.91 (0.68–1.21) | 0.182 | 0.66 (0.35–1.22) | ||
| C-T | – | – | – | – | ||
Pobs, observed P value; Padj, P value adjusted for age, gender, hypertension, diabetes mellitus and smoking history; OR, odds ratio after the adjustment.