Table 3.
Subgroup Analysis of Diabetic Patients
| Variable | DM Duration, Years | HbA1c, % | DR, n (%) | CCT §, μm | Corneal Volume, mm3 | ECD, Cell/mm2 | CV of Cell Size, % | Hexagonal Cells, % | |
|---|---|---|---|---|---|---|---|---|---|
| DM Duration, years | <10 (n=30) | 4.9 ± 2.4 | 6.6 ± 0.8 | 4 (13%) | 557 ± 38 | 60.4 ± 4.4 | 2404 ± 295 | 35.8 ± 5.2 | 55.8 ± 8.1 |
| ≥ 10 (n=30) | 17.1 ± 7.0* | 7.4 ± 1.3* | 14 (47%) | 559 ± 32 | 60.9 ± 3.6 | 2347 ± 314 | 35.1 ± 6.6 | 55.9 ± 7.0 | |
| HbA1c Levels, % | < 7.0(n=31) | 7.6 ± 5.8 | 6.2 ± 0.5 | 5 (16%) | 554 ± 39 | 60.0 ± 4.2 | 2370 ± 329 | 35.6 ± 6.5 | 54.9 ± 8.7 |
| ≥ 7.0(n=29) | 14.6 ± 8.6* | 7.9 ± 1.0* | 13 (45%) | 562 ± 29 | 61.3 ± 3.8 | 2381 ± 279 | 35.3 ± 5.3 | 56.8 ± 5.8 | |
| DR | No (n=42) | 8.4 ± 6.1 | 6.8 ± 1.1 | – | 556 ± 36 | 60.4 ± 4.3 | 2395 ± 310 | 35.7 ± 5.6 | 54.8 ± 7.0 |
| Yes (n=18) | 17.1 ± 8.9* | 7.4 ± 1.3* | – | 563 ± 32 | 61.3 ± 3.3 | 2330 ± 293 | 34.9 ± 6.7 | 58.2 ± 8.2 | |
Notes: Continuous variables are reported as mean ± standard deviation. *P <0.05, statistical significance. § CCT measured by Pentacam at corneal vertex.
Abbreviations: CV, coefficient of variation of cell size; DM, diabetes mellitus; DR, diabetic retinopathy; ECD, endothelial cell density; CCT, central corneal thickness; HbA1c, glycated hemoglobin; mm, millimeter; mm2, square millimeter; mm3, cubic millimeter; μm, micrometer.