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EC50 values and maximum activity (MA) of benznidazole, nifurtimox and posaconazole against H10 clones.
| Clone | Benznidazole |
Nifurtimox |
Posaconazole |
|||
|---|---|---|---|---|---|---|
| EC50 (μM) | MA (%) | EC50 (μM) | MA (%) | EC50 (nM) | MA (%) | |
| H10–S | 31.4 | 96.2 | 3.5 | 95.2 | 2.1 | 85.7 |
| H10-LT | 41.8 | 88.2 | 3.3 | 94.4 | 1.2 | 75.9 |
| H10-R | 42.5 | 83.3 | 6.1 | 83.6 | 17,159 | 65.5 |
| H10-R-NP | 28.0 | 89.7 | 2.4 | 95.2 | 1,811 | 80.5 |
