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Anti-T. cruzi activity of amphotericin B, azoles, fenarimols and oxaborole against the sensitive and the resistant H10 clone.
| H10–S |
H10-R |
|||
|---|---|---|---|---|
| EC50 (μM) | MA (%) | EC50 (μM) | MA (%) | |
| Fluconazole | 9.3 | 68 | NDa | 30 |
| Itraconazole | 0.1 | 102 | 6.2 | 87 |
| Voriconazole | 0.2 | 73 | NDa | 56 |
| Ketoconazole | 0.04 | 65 | 4.5 | 63 |
| BS967/UDD | 0.5 | 91 | 22.8 | 65 |
| BS1246/UDO | 0.2 | 86 | 17.7 | 72 |
| Amphotericin B | NDa | 36 | NDa | 33 |
| AN4169 | 1.8 | 89 | 0.7 | 84 |
aND indicates that the value could not be calculated. Data from two independent experiments.
