Table 2.
KEGG Pathways Analysis of Three Key Models Selected from the PPI Network
| Term | Description | Count | P-value |
|---|---|---|---|
| Model 1 | |||
| hsa04110 | Cell cycle | 5 | 3.38E-06 |
| Model 2 | |||
| hsa05200 | Pathways in cancer | 7 | 1.21E-05 |
| hsa04916 | Melanogenesis | 5 | 1.28E-05 |
| hsa04310 | Wnt signaling pathway | 5 | 4.59E-05 |
| hsa05217 | Basal cell carcinoma | 4 | 7.22E-05 |
| hsa04550 | Pathways regulating pluripotency of stem cells | 4 | 0.001208 |
| hsa04390 | Hippo signaling pathway | 4 | 0.001503 |
| hsa05205 | Proteoglycans in cancer | 4 | 0.003362 |
| hsa05166 | HTLV-I infection | 4 | 0.006586 |
| hsa04062 | Chemokine signaling pathway | 3 | 0.034067 |
| Model 3 | |||
| hsa00830 | Retinol metabolism | 4 | 4.16E-05 |
| hsa00350 | Tyrosine metabolism | 3 | 0.000691 |
| hsa00982 | Drug metabolism - cytochrome P450 | 3 | 0.002595 |
| hsa04530 | Tight junction | 3 | 0.004214 |
| hsa04670 | Leukocyte transendothelial migration | 3 | 0.007264 |
| hsa05160 | Hepatitis C | 3 | 0.009625 |
| hsa04514 | Cell adhesion molecules (CAMs) | 3 | 0.01092 |
| hsa00071 | Fatty acid degradation | 2 | 0.047837 |
Abbreviations: KEGG, Kyoto Encyclopedia of Genes and Genomes; Wnt, wingless integrated; PPI, protein–protein interaction.