Table 7. Summary of different comparative results for MTHFR A1298C polymorphisms in ovarian cancer.
| Genotypes | Overall and subgroup | Participants | OR and 95%CI | Z value | P value | I2 (%) | Effect model# |
|---|---|---|---|---|---|---|---|
| CC vs. AC+AA | Overall | 6,860 | 1.09 [0.92, 1.28] | 1.01 | 0.31 | 0 | F |
| Caucasian | 6,460 | 1.06 [0.90, 1.26] | 0.74 | 0.46 | 0 | F | |
| CC+AC vs. AA | Overall | 6,860 | 1.00 [0.91, 1.10] | 0.06 | 0.95 | 0 | F |
| Caucasian | 6,460 | 0.99 [0.90, 1.09] | 0.19 | 0.85 | 0 | F | |
| AC vs. AA+CC | Overall | 6,860 | 0.97 [0.88, 1.07] | 0.67 | 0.5 | 0 | F |
| Caucasian | 6,460 | 0.97 [0.88, 1.07] | 0.64 | 0.52 | 0 | F | |
| CC vs. AA | Overall | 3,974 | 1.08 [0.91, 1.27] | 0.85 | 0.4 | 0 | F |
| Caucasian | 3,730 | 1.05 [0.88, 1.25] | 0.57 | 0.57 | 0 | F | |
| C vs. A | Overall | 13,720 | 1.02 [0.94, 1.09] | 0.41 | 0.68 | 0 | F |
| Caucasian | 12,920 | 1.01 [0.93, 1.09] | 0.19 | 0.85 | 0 | F |
#
Effect model includes fixed-effect model (F) and random-effect model (R).