Figure 5.
Composition of stroma and tumor of PAC006. (A) Representative Hematoxylin and eosin (H&E) staining of tumor tissues at the end of treatment (Scale bar 50 µm). (B) Tumor sections were stained with antibody for human Cytokeratin-pan antigen (PAN-CK) to visualize the area occupied by the human tumor (Scale bar 50 µm). (C) Quantification of macrophage phenotype by immunofluorescence (M1: combination of MHCIIhigh and CD206low, M2: mouse-specific macrophage marker F4/80 together with CD206high). Tumor sections of 4 animals per group were analysis per condition (see also Supplementary File).