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. 2020 Jul 20;6(2):00192-2019. doi: 10.1183/23120541.00192-2019

TABLE 3.

Urinary cotinine concentrations in healthy controls (HC), COPD patients and asthma patients

First author [ref.] Patients Smokers versus nonsmokers SHS
Cut-off Sns Spc Cut-off Sns Spc
HC Goniewicz [10] 601 31.5 ng·mL−1 97.1% 93.9% See table 4 NA NA
Kim [11] 11 629 164 ng·mL−1 93.2% 95.7% NA NA NA
COPD Chen [6] 78 NA NA NA NA NA NA
Asthma Fernandes [9] 996 196.98 μg·g−1 NA NA NA NA NA

The cut-off showed for asthmatic patients is normalised on serum creatinine, expressed in grams. Sns: sensitivity; Spc: specificity; SHS: second-hand smoke; NA: not available.