Figure 6.

Characterization of lymphoid tissue-specific B cell populations

(A) Experimental workflow (n = 11 donors).

(B) Violin plots of molecules significantly differentially expressed by at least two tissues (p < 0.005).

(C) IgH isotype usage by tissue. ND denotes “not determined”; IgMD denotes co-expression of IgM and IgD.

(D) Subset composition by tissue.

(E) Manhattan distance between each tissue based on subset composition.

(F) Biaxial of B cells colored as GC or other.

(G) Biaxial of B cells colored as CD39⁺ tonsillar or other.

(H) UMAP plot generated from an equal subsampling by tissue, then an equal subsampling by subset.