Table 2.
List of linear mixed effects models (for continuous variables) and logistic mixed effects models (for dichotomous variables). All models were adjusted for age and sex. Bolded and red values indicate statistical significance (p < 0.05). PinQ = Pediatric Incontinence Quality of Life questionnaire, BBD = bowel and bladder dysfunction, QmaxFI = maximum flow index, QavgFI = mean flow index
|
Linear mixed-effects models |
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| Estimate (increase in 100 units of pons volume) | P value (adjusted for age and sex) | Observations | Unique patients | |
| Post-void bladder volume | −0.077 | 0.972 | 64 | 24 |
| Functional bladder capacity | 3.341 | 0.263 | 47 | 24 |
| Maximum urine flow index (QmaxFI) | 0.005 | 0.280 | 56 | 22 |
| Mean urine flow index (QavgFI) | −0.003 | 0.577 | 43 | 22 |
| Voids per day | −0.026 | 0.664 | 27 | 15 |
| Bowel movements per day | 0.021 | 0.186 | 16 | 10 |
| Bristol stool score | −0.002 | 0.868 | 16 | 10 |
| PinQ score | −0.442 | 0.011 | 40 | 20 |
| Toronto BBD score | −0.218 | 0.062 | 41 | 21 |
| Compass-31 score | −0.187 | 0.254 | 22 | 16 |
| Hemoglobin A1c | −0.024 | 0.219 | 96 | 25 |
|
Logistic mixed-effect models |
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| Odds ratio (increase in 100 units of total pons volume) | P value (adjusted for age and sex) | Observations | Unique patients | |
| Increased post-void residual | 0.958 | 0.048 | 64 | 24 |
| Disordered uroflowmetry | 0.985 | 0.614 | 56 | 22 |
| Subjective urinary frequency * | 0.902 | 0.219 | 21 | 11 |
| Subjective urinary urgency | 0.873 | 0.089 | 17 | 10 |
| Subjective urinary incontinence | 1.055 | 0.646 | 17 | 10 |
| Diagnosis of diabetes insipidus | 0.208 | 0.046 | 97 | 25 |
| Objective polyuria on voiding diary | 0.913 | 0.148 | 30 | 15 |
Models devolved into fixed effects models