Table 2.
Univariate and multivariate Cox regression analyses of risk factors for overall survival time in the ZZU HCC cohort.
| Variable | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | |
| Sex (male vs. female) | 1.145 (0.715-1.831) | 0.573 | ||
| Age (<50 vs. ≥50 years) | 0.968 (0.651-1.440) | 0.874 | ||
| Liver cirrhosis (absent vs. present) | 1.557 (0.834-2.907) | 0.165 | ||
| AFP (≥20 ng/ml vs. <20 ng/ml) | 0.760 (0.516-1.120) | 0.165 | ||
| Tumour multiplicity (single vs. multiple) | 1.023 (0.653-1.604) | 0.919 | ||
| Maximal tumour size (<5 cm vs. ≥5 cm) | 1.019 (0.694-1.497) | 0.923 | ||
| Portal vein thrombosis (absence vs. gross) | 0.543 (0.327-0.903) | 0.019∗ | 0.987 (0.566-1.721) | 0.963 |
| TNM stage (I-II vs. III-IV) | 0.317 (0.213-0.472) | 0.000∗∗ | 0.332 (0.215-0.513) | 0.000∗∗ |
| UGP2 level (low vs. high) | 1.873 (1.245-2.819) | 0.003∗ | 1.754 (1.162-2.648) | 0.007∗ |
Notes: ∗P < 0.05, ∗∗P < 0.001. Abbreviations: AFP: alpha-fetoprotein; TNM: tumour-node-metastasis; HR: hazard ratio; CI: confidential interval.