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. 2020 Jul 11;2020:2153571. doi: 10.1155/2020/2153571

Figure 6.

Figure 6

Effects of paeoniflorin on plasma and hippocampus monoamines of rats subjected to FST. (a) Plasma 5-HT, NE, and DA remarkably reduced in the M group compared with the NC group, while F and P can reverse these changes. (b) Hippocampus 5-HT and NE obviously decreased in the M group, while F and P can reverse these changes. (c) Hippocampus DA significantly decreased in the M group, while F and P can reverse this change. Compared with the NC group, ∗∗p < 0.01. Compared with the M group, ##p < 0.01 and #p < 0.05. NC, normal control; M, model; F, fluoxetine; P, paeoniflorin; 5-HT, 5-hydroxytryptamine; NE, norepinephrine; DA, dopamine; FST, forced swimming test.