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. 2020 Jun 27;21(13):4569. doi: 10.3390/ijms21134569
5caC 5-carboxylcytosine
5fC 5-formylcytosine
5hmC 5-hydroxymethylcytosine
5mC 5-methylcytosine
AC/ADC Adenocarcinoma
ALK Anaplastic lymphoma kinase
AUC Area under the receiver operating characteristic (ROC) curve
BAL Bronchoalveolar lavage
BRAF B-raf proto-oncogene
BS-Seq Bisulfite conversion followed by sequencing
CEA Carcinoembryonic antigen
cfDNA Cell-free circulating DNA
CGH Comparative genomic hybridization
ChIP Chromatin immunoprecipitation
CIS Carcinoma in situ
CNV Copy number variation
CTC Circulating tumor cell
ctDNA Cell-free tumor DNA
ddPCR Droplet digital polymerase chain reaction
DFS Disease free survival
DNMT DNA methyltransferase enzyme
dNTP Deoxynucleotide
DR Death receptor
EGFR Epidermal growth factor receptor
ELISA Enzyme-linked immunosorbent assay
ERBB2 Erb-B2 receptor tyrosine kinase 2
FHIT Fragile histidine triad diadenosine triphosphatase
FISH Fluorescence in situ hybridization
HER2 Human epidermal growth factor receptor 2
HNPCC Hereditary non-polyposis colon cancer
HPLC High-performance liquid chromatography
HUGO Human Genome Organization
IHC Immunohistochemistry
ISH In situ hybridization
KRAS Kirsten rat sarcoma viral oncogene
LDCT Low-dose computer tomography
LOH Loss of heterogeneity
Mb Megabase
MeFISH Methylation-specific fluorescence in situ hybridization
MET Mesenchymal-epithelial transition factor
MLPA Multiplex ligation-dependent probe amplification
MSI Microsatellite instability
NA Not available
NGS Next-generation sequencing
NSCLC Non-small cell lung carcinoma/Non-small cell lung cancer
NSE Neuron-specific enolase
OS Overall survival
PCR Polymerase chain reaction
PI Proximal-inflammatory
PP Proximal-proliferative
PPV Positive predictive value
PTM Posttranslational modification
qPCR Quantitative real-time polymerase chain reaction
RET Rearranged during transfection
RISC RNA-induced silencing complex
ROC Receiver operating characteristic
ROS1 C-ros oncogene 1
RT-PCR Reverse-transcription polymerase chain reaction
SCC Squamous cell carcinoma/Squamous cell cancer
SCCA Squamous cell carcinoma antigen
SCLC Small cell lung carcinoma/Small cell lung cancer
SCNA Somatic copy number alteration
SNP Single nucleotide polymorphism
SNV Single nucleotide variant
TCGA The Cancer Genome Atlas
TKI Tyrosine kinase inhibitor
TMB Tumor mutation burden
TNM TNM Classification of Malignant Tumors (tumor-lymph nodes-metastasis)
TRU Terminal respiratory unit
WES Whole-exome sequencing
WGS Whole-genome sequencing