Figure 2.

The effect of a single dose of ketamine (Ket) and Ro 25–6981 on sucrose intake in rats subjected to zinc deficiency. (A) Experimental schedule of drug treatments and behavioral test; (B) ketamine (10 mg/kg; i.p.) and Ro 25–6981 (10 mg/kg; i.p.) were administered 60 min before the test. Data were analyzed by two-way ANOVA and the Newman–Keuls multiple comparisons test. Values are expressed as mean ± S.E.M. Two-way ANOVA showed significant interaction [F (2, 44) = 5.555; p = 0.0071], the significant effect of ZnD [F (2, 44) = 7.268; p = 0.0019] and the non-significant effect of treatment [F (1, 44) = 0.6351, p = 0.4298]. * p < 0.05 vs. ZnA + Veh; ^### p < 0.001 vs. ZnD + Veh (n = 8–9).