ACN	Acetonitrile
AST	Astrocytoma
CSF	Cerebrospinal fluid
DIA	Data independent acquisition
DE	Differential expression/differentially expressed
EV	Extracellular vesicle
FA	Formic acid
GBM	Glioblastoma
GIV	Grade IV
GII-III	Grade II–III
HC	Healthy control
HILIC	Hydrophilic liquid chromatography
HPLC	High performance liquid chromatography
ID	Identification
IDA	Information dependent acquisition
IDH	Isocitrate dehydrogenase
iRT	Indexed retention time
LC-	Liquid chromatography tandem mass spectrometry
MEN	Meningioma
MRI	Magnetic resonance imaging
MS	Mass spectrometry
Mut	Mutation
NA	Not applicable
NTA	Nanoparticle tracking analysis
PBS	Phosphate buffered saline
PCA	Principal component analysis
RANO	Response Assessment in Neuro-Oncology
RT	Room temperature
SEC	Size exclusion chromatography
SWATH	Sequential window acquisition of all theoretic fragment ion spectra
TCEP	Tris(2-carboxyl) phosphine
TEAB	Tetraethylammonium bicarbonate
TEM	Transmission electron microscopy
TFA	Trifluoroacetic acid
TMZ	Temozolomide
TRiC	T-complex protein 1 ring complex
wt	Wild-type