Table 5.
Three-way interaction analysis by the studied inflammatory biomarkers.
| Factor a | CRP (n = 100) κ | IL-6 (n = 100) κ | TNF-α (n = 100) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SS | df | MS | F | p-value | SS | df | MS | F | p-value | SS | df | MS | F | p-value | |
| A | 0.814 | 1 | 0.814 | 2.126 | 0.148 | 0.208 | 1 | 0.208 | 4.123 | 0.045 * | 0.065 | 1 | 0.065 | 0.389 | 0.534 |
| B | 0.613 | 1 | 0.613 | 1.601 | 0.209 | 0.285 | 1 | 0.285 | 5.639 | 0.020 * | 0.303 | 1 | 0.303 | 1.809 | 0.182 |
| C | 7.620 | 1 | 7.620 | 19.913 | 0.001 * | 1.839 | 1 | 1.839 | 36.370 | 0.000 * | 0.053 | 1 | 0.053 | 0.317 | 0.575 |
| A × B | 0.128 | 1 | 0.128 | 0.335 | 0.564 | 0.347 | 1 | 0.347 | 6.869 | 0.010 * | 0.001 | 1 | 0.001 | 0.004 | 0.951 |
| A × C | 0.154 | 1 | 0154 | 0.402 | 0.528 | 0.002 | 1 | 0.002 | 0.030 | 0.862 | 0.657 | 1 | 0.657 | 3.924 | 0.051 |
| B × C | 0.004 | 1 | 0.004 | 0.012 | 0.914 | 0.003 | 1 | 0.003 | 0.056 | 0.814 | 0.036 | 1 | 0.036 | 0.214 | 0.645 |
| A × B × C | 0.482 | 1 | 0.482 | 1.259 | 0.265 | 0.038 | 1 | 0.038 | 0.757 | 0.386 | 0.516 | 1 | 0.516 | 3.083 | 0.082 |
| SSE | 34.821 | 91 | 0.383 | 4.651 | 92 | 0.051 | 15.231 | 91 | 0.167 | ||||||
| SST | 141.576 | 99 | 8.030 | 100 | 150.358 | 99 | |||||||||
* p <0.05. aA, B, and C represent OSAS severity, sex, and obesity, respectively. κ The analysis was based on log10 transformation. Abbreviations: CRP, C-reactive protein; df, degree of freedom; F, F-value; IL-6, interleukin-6; MS, mean square; SS, total sum of square of deviation from mean; SSE, error sum of square; SST, total sum of square; TNF-α, tumor necrosis factor-α.