| PD | Parkinson’s Disease |
| α-Syn | α-synuclein |
| ROT | rotenone |
| PQ | paraquat |
| MB | maneb |
| ROS | reactive oxygen species |
| H2O2 | hydrogen peroxide |
| GSH | Glutathione |
| BBB | blood brain barrier |
| CNS | central nervous system |
| ARs | adenosine receptors |
| MAO-B | monoamine oxidase-B |
| Nrf2 | nuclear factor erythroid 2-related factor 2 |
| PGC-1α | peroxisome proliferator-activated receptor-gamma coactivator 1-α |
| KO | knockout |
| PDE | phosphodiesterase |
| A2AR | adenosine 2A receptor |
| PKA | protein kinase A |
| TNF-α | tumor necrosis factor alpha |
| L-DOPA | L-3,4-dihydroxyphenylalanine |
| GABA | γ-aminobutyric acid |
| A1R | adenosine 1 receptor |
| MPTP | N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine |
| 6-OHDA | 6-hydroxydopamine |
| qRT-PCR | quantitative real-time polymerase chain reaction |
| DOPAC | 3,4 dihydroxyphenylacetic acid |
| CSC | 8-(-3-chlorostyryl)-caffeine |
| AIMs | abnormal involuntary movements |
| THP | trihexyphenidyl |
| ESS | Epworth Sleepiness Scale |
| UPDRS | unified Parkinson’s Disease rating scale |
| HC | healthy control |
| HPFS | Study of Health Professionals |
| NHS | Nurses’ Health Study |