Table 1.
Cell type specific marker genes for vascular cell types from single cell data. Marker genes were derived from References [3,10,29]. Endothelial cells (ECs); smooth muscle cells (SMCs).
| Cell Type | Marker Genes (scRNA-seq) |
|---|---|
| all ECs | Kdr (Vegfr2), Cdh5, Pecam1 (CD31), Tie1, Flt1, Vwf, Icam2 (CD102) |
| arterial ECs | Hey1, Fbln5, Vegfc, Sema3g, Cytl1, Gkn3, Stmn2, Sox17, Bmx, Efnb2 |
| venous ECs | Nr2f2, Lcn2, Vwf, Emcn, Scl38a5, Cfh, Apoe |
| capillary ECs | Mfsd2a, Rgcc, Ramp3, Cd300lg, Tgfb2 (A), Glul (A), Tfrc (V), Car4 (V) |
| lymphatic ECs | Flt4, Prox1, Mmm1, Ccl21a, Mmrn1, Fgl2, Lyve1, Thy1 |
| all SMCs | Myh11, Acta2, Tagln, Vim, Des, Myl9, Pdgfrb, Cspg4, Tcf21 |
| arterial SMCs | Cnn1 |
| arteriole SMCs | Acta2, Tagln-high |
| venous SMCs | Acta2, Tagln-low |
| pericytes | Pdgfrb, Cspg4, Des, Abcc9, Vtn, Anpep, Rgs5 |
| fibroblasts | Dcn, Tcf21, Bgn, Eln, Col1a1, Col1a2, Pdgfra |