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. 2020 Jun 29;21(13):4604. doi: 10.3390/ijms21134604

Figure 4.

Figure 4

MSCs roles in each phase of the wound-healing process. Inflammatory phase, MSCs inhibit the proliferation of T cells, TNF α, IFNγ and modulate cytokine secretion. Proliferative phase, MSCs augment keratinocyte, endothelial cell, fibroblast recruitment and differentiation and facilitate GF secretion. Remodelling phase MSCs improve collagen quality.