Figure 6.
Effect of 4′-F-PCP on the immunoreactivities of pERK, pCREB, c-Fos, and FosB/ΔFosB proteins in the NAc of 4′-F-PCP-self-administered rats under the PR schedule. (A–F) Immunoreactivities of pERK, pCREB, c-Fos, and FosB/ΔFosB proteins in the NAc after saline or 1.0 mg/kg/infusion 4′-F-PCP self-administration under the PR schedules of reinforcement. Asterisks *, **, and *** indicate p < 0.05, p < 0.01, and p < 0.001, respectively, vs. saline controls. SAL: saline. n = 4–6 per group.