ADC	Antibody Drug Coniugated
BC	Breast Cancer
BL1/2	Basal-Like 1/2
BRCA1/2	BReast CAncer type 1 and Type 2
CSCs	Cancer Stem Cells
CTCs	Circulating Tumor Cells
dMMR	Mismatch Repair deficiency
DSBs	DNA Double Strand Breaks
DCs	Dendritic Cells
DFS	Disease Free Survival
EMT	Epithelial Mesenchymal Transition
ER	Estrogen Receptor
FDA	Food and Drug Administration
FFPE	Formalin-fixed paraffin embedded
GEP	Gene Expression Profile
gBRCAm	germline BRCA mutations
GPNMB	Glycoprotein non-metastatic b
HBOC	Hereditary Breast and Ovarian Cancer Syndrome
HRD	Homologous Recombination Deficiency
HRD-LOD	HRD-Loss of Heterozygosity
HRD-LST	HDR-Large Scale Transition
HRD-TAI	HDR-Telomeric Allelic Imbalance
HER2	Human Epidermal Growth Factor Receptor 2
HR	Homologous Recombination
HRR	Homologous Recombination Repair
IC	Immune Cells
ICI	Immune Checkpoint Inhibitor
IM	Immunomodulatory
LAG3	Lymphocyte-associated gene 3
LAR	Luminal Androgen Receptor
MAP	Mitogen-Activated Protein
MBC	Metastatic Breast Cancer
MHC	Major Histocompatibility Complex
MMAE	Microtubule-disrupting agent monomethyl auristatin E
MMR	Mismatch Repair
MSI	Microsatellite Instability
MSI-H	High Microsatellite Instability
MSL	Mesenchymal Stem-Like
mTOR	Mammalian Target Of Rapamycin
mTORC1	mTOR complex 1
NGS	Next Generation Sequencing
NHEJ	Non-Homologous End Joining
NK	Natural Killer
ORR	Objective Response Rate
OS	Overall Survival
OXPHOS	Oxidative Phosphorylation
pCR	Pathological Complete Response
PARP	Poly ADP-ribose polymerase
PARPi	Poly ADP-ribose polymerase Inhibitors
PD-1	Programmed Cell Death-1
PD-L1	Programmed Cell Death Ligand-1
PDX	Patient-Derived-Xenograft
PFS	Progression Free Survival
PI3K	Phosphatidylinositol 3-kinase
PIK3CA	Phosphatidylinositol-4, 5-bisphosphate 3-kinase, catalytic subunit, alpha
PIP3	Phosphatidylinositol (3,4,5)-trisphosphate
PTEN	Phosphatase and Tensin Homolog
PR	Progesterone Receptor
RCB	Residual Cancer Burden
sBRCAm	Somatic BRCA mutations
TC	Tumor Cells
TIL	Tumor Infiltrating Lymphocytes
TMB	Tumor Mutational Burden
TNBC	Triple Negative Breast Cancer
UNS	Unstable