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. 2020 Jul 2;21(13):4734. doi: 10.3390/ijms21134734

Figure 2.

Figure 2

WB analysis of the effects of DSPP and MMP20 silencing on αvβ3, αvβ6, and VEGF levels. (a) Downregulation of αvβ3 in shDSPP (50%), shMMP20 (55%), and shDM (45%) were significant (p < 0.05) when compared to the control. (b) Downregulation of αvβ6 in shDSPP (48%), shMMP20 (38%), and shDM (46%) were significant (p < 0.01, 0.001) when compared to the control. (c) Downregulation of VEGF in shDSPP (48%), shMMP20 (46%), and shDM (50%) were significant (p < 0.05) when compared to the control. Beta actin was used as the internal control. Values are given as mean ± SE for 3 independent experiments. shC = Scrambled Control; shDSPP = DSPP Silenced OSC2 cells; shMMP20 = MMP20 Silenced OSC2 cells; DM = Combined DSPP–MMP20 Silenced OSC2 cells; * p < 0.05; ** p < 0.01; *** p < 0.001.