Table 4.
RD values for protofibrils. RD value calculated for a 3D Gaussian distribution encapsulating the whole protofibril. The values of the parameters σX, σY, and σZ are given for expressing the aggregate orientation. Z axis oriented according to the long axis of the fibril. A set of chains included in the protofibrils is given. A central chain that occupies a position in the XY plane is given in parenthesis. Value provided as bold—status consistent with idealized distribution.
| Protein | Chains | RD | σX | σY | σZ |
|---|---|---|---|---|---|
| Aβ(11–42) (2MXU) | A-L (F) | 0.655 | 10.06 | 13.61 | 13.84 |
| Aβ(1–40) (2MVX) | A, B, C, D, E (C) | 0.619 | 13.87 | 12.42 | 8.34 |
| Aβ(15–40) (2MPZ) | B, E, H, K, N, Q, T, W, Z | 0.683 | 12.04 | 10.61 | 11.13 |
| Aβ(11–42)S (5KK3) | A-I (E) | 0.525 | 12.38 | 10.46 | 13.98 |
| TAU (5O3L) | A, C, E, G, I (E) | 0.604 | 14.65 | 15.42 | 8.28 |
| ASyn (2N0A) | A- J (E) | 0.576 | 18.94 | 18.7 | 14.14 |
| 30–100 | 0.486 | 13.48 | 11.88 | 14.19 | |
| 47–100 | |||||
| ImVA (6HUD) | A-E (C) | 0.724 | 15.62 | 12.5 | 9.03 |
| Aβ(15–40)51 (2MPZ) | 51 chains | 0.847 | 15.1 | 14.76 | 47.11 |