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Lipid extracts of irradiated PBMCs suppress inflammation in primary macrophages. Murine bone marrow-derived macrophages were exposed to 1 × 107 secretome and equivalent lipids. Inflammation was induced by exposure to 100 ng/mL LPS (A) or 5% saliva (B). Expression of inflammatory genes is indicated in percentage (%) compared to stimulated controls (100%). Dot-blots represent independent experiments. p-values are based on a Mann–Whitney test.
