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. 2020 Jun 30;21(13):4635. doi: 10.3390/ijms21134635

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Tukey boxplots of immune cells CD8⁺ T-cells, Natural Killer (NK) activated cells, M1 and M2 macrophages, T-follicular helper cells, T-regulatory cells, and cytolytic activity (CYT) in GR-high and GR-low breast cancer using CIBERSORT algorithm in METABRIC and TCGA cohorts (A) in the entire cohort (Whole) and (B) in estrogen receptor (ER)-positive/human epidermal growth factor receptor (HER2)-negative and triple negative (TNBC) subtypes. The cut-off of top and bottom quartile of NR3C1 expression was considered as GR high and GR low in the entire cohort and also in the respective subtypes. Y-axis shows the fraction of cells with GR-low or GR-high expression. Boxes depict medians and interquartile ranges. Depicted p values are calculated using one-way ANOVA.