Table 1.

Associations Between Mother’s and Children’s Polygenic Score (PGS) for Educational Attainment and Prenatal Exposures (From Separate Models)

Outcome	Maternal PGS		Child PGS		n
	β	95% CI	β	95% CI
Health composite	0.089	[0.046, 0.132]	0.048	[−0.002, 0.097]	1,986
Body mass index	−0.030	[−0.077, 0.017]	−0.021	[−0.074, 0.032]	1,903
Mental health	−0.009	[−0.056, 0.038]	−0.001	[−0.055, 0.053]	1,910
Vitamin use	0.060	[0.014, 0.107]	0.092	[0.042, 0.143]	1,986
Indirect smoke exposure	−0.076	[−0.118, −0.034]	−0.050	[−0.099, −0.002]	1,984
Smoking	−0.108	[−0.151, −0.065]	−0.048	[−0.096, 0.000]	1,986
Alcohol consumption	0.067	[0.021, 0.113]	0.034	[−0.017, 0.085]	1,986
Caffeine use	−0.070	[−0.118, −0.023]	−0.008	[−0.056, 0.040]	1,742
Drug use	−0.013	[−0.056, 0.031]	0.014	[−0.040, 0.069]	1,923
Sleep problems	−0.005	[−0.051, 0.041	0.001	[−0.052, 0.053]	1,907
SES composite	0.156	[0.114, 0.198]	0.096	[0.048, 0.143]	1,986
Maternal education	0.206	[0.162, 0.250]	0.070	[0.019, 0.121]	1,809
Single	−0.081	[−0.123, −0.039]	−0.086	[−0.135, −0.037]	1,985
Employed	0.092	[0.049, 0.136]	0.036	[−0.015, 0.086]	1,986
Maternal leave	−0.019	[−0.069, 0.031]	−0.026	[−0.080, 0.029]	1,554
Neighborhood deprivation	−0.067	[−0.112, −0.022]	−0.044	[−0.094, 0.006]	1,935
Financial difficulty	−0.030	[−0.076, 0.017]	−0.058	[−0.112, −0.004]	1,984
Receipt of governmental benefits	−0.102	[−0.145, −0.059]	−0.052	[−0.104, −0.001]	1,984

Note: The rightmost column shows individual ns. For associations with maternal PGS, analyses controlled for age and 10 principal components. For associations with child PGS, analyses controlled for maternal PGS, age, and 10 principal components. CI = confidence interval; SES = socioeconomic status.