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. 2020 Jul 20;18:99. doi: 10.1186/s12951-020-00653-y

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — a Cell viabilities of HGC-27 cells after treated with single HMON@CuS/Gd, HMON@CuS/Gd plus NIR and HMON@CuS/Gd plus NIR on ice, using CCK-8 assay. b LDH leakage of HGC-27 cells after treated with single HMON@CuS/Gd, HMON@CuS/Gd plus NIR and HMON@CuS/Gd plus NIR on ice, using LDH assay. c CCK-8 assay of HGC-27 cells after treated with single HMON@CuS/Gd, HMON@CuS/Gd plus NIR, HMON@CuS/Gd plus NIR on ice or HMON@CuS/Gd plus external heating. d LDH leakage assay of HGC-27 cells after treated with single HMON@CuS/Gd, HMON@CuS/Gd plus NIR, HMON@CuS/Gd plus NIR on ice or HMON@CuS/Gd plus external heating. e The CCK-8 assay of GES-1 cells after incubation with HMON@CuS/Gd NPs for 24 h. f The confocal laser scanning microscopy (CLSM) images of RAW264.7 murine macrophage-like cells after incubation with HMON@CuS/Gd for 24 h. Scale bar: 20 μm. Data are shown as mean ± SD, n = 3. * indicates P < 0.05, *** indicates P < 0.001