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. 2020 Jul 20;21:661. doi: 10.1186/s13063-020-04428-6
Primary trial registrations

All trials registered prospectively with ISRCN.

NEON Trial: ISRCTN11152837, registered 13 August 2018, http://www.isrctn.com/ISRCTN11152837

NEON-C Trial: ISRCTN76355273, registered 9 January 2020, http://www.isrctn.com/ISRCTN76355273.

NEON-O Trial: ISRCTN63197153, registered 9 January 2020, http://www.isrctn.com/ISRCTN63197153.

Secondary identifying numbers

IRAS ID: 249015

REC ref.: 19/EM/0326

Source of monetary support National Institute for Health Research (NIHR) Programme Grant for Applied Research (RP-PG-0615-20016)
Primary Sponsor

Nottinghamshire Healthcare NHS Foundation Trust

Contact: Mark Howells

Duncan Macmillan House, Porchester Road, Nottingham NG3 6AA, 0115 9691300

Mark.Howells@nottshc.nhs.uk or Research@nottshc.nhs.uk

Secondary Sponsor Not applicable
Chief Investigator

Professor Mike Slade

Institute of Mental Health, University of Nottingham Innovation Park, Triumph Road, Nottingham, NG7 2TU

m.slade@nottingham.ac.uk

Contact for public enquiries

Stefan Rennick-Egglestone

Institute of Mental Health, University of Nottingham Innovation Park, Triumph Road, Nottingham, NG7 2TU

stefan.egglestone@nottingham.ac.uk

Contact for scientific enquiries

Professor Mike Slade

Institute of Mental Health, University of Nottingham Innovation Park, Triumph Road, Nottingham, NG7 2TU

m.slade@nottingham.ac.uk

Public title NEON (Narrative Experiences Online) study: trials of an online intervention
Scientific title NEON (Narrative Experiences Online) study: trials of an online intervention
Countries of recruitment England
Health condition(s) or problem(s) studied

NEON Trial: Psychosis

NEON-O Trial: Non-psychosis mental health problems

NEON-C Trial: Not a study of a health condition

Interventions

Intervention arm: treatment as usual plus access to online recovery narratives for 1 year

Control arm: treatment as usual for 1 year, followed by access to recorded recovery narratives

Inclusion criteria See main body of protocol
Study type All trials are interventional, with no masking and 1:1 randomised allocation using a sequence generated through permuted blocks randomisation
Date of first enrolment 9th March 2020
Target sample size

NEON Trial: 683

NEON-C Trial: 100

NEON-O Trial: 100

Recruitment status Recruitment opened same day as protocol submission
Primary outcome Manchester Short Assessment of Quality of Life at 52 weeks after baseline.
Secondary outcomes CORE-10, Herth Hope Index, Mental Health Confidence Scale, Meaning in Life Questionnaire, all at 52 weeks after baseline.
Recruiting organisations

Nottinghamshire Healthcare NHS Foundation Trust

Principal investigator: Professor Mike Slade m.slade@nottingham.ac.uk

Principal contact: Stefan Rennick-Egglestone stefan.egglestone@nottingham.ac.uk

Cornwall Partnership NHS Foundation Trust

Principal Investigator: Ruth Bishop ruth.bishop2@nhs.net

Principal contact: Alan Beattie alan.beattie1@nhs.net

Derbyshire Healthcare NHS Foundation Trust

Principal Investigator: Dr. Soma Datta somadatta@nhs.net

Principal contact: Andy Dingwall andy.dingwall@nhs.net

Devon Partnerships NHS Foundation Trust

Principal Investigator: Dr. Zara Bowling zara.bowling@nhs.net

Principal contact: Christina Burke-Trees c.burke-trees@nhs.net

East London NHS Foundation Trust

Principal Investigator: Professor Stefan Priebe s.priebe@qmul.ac.uk

Principal contact: Zivile Jakaite zivile.jakaite@nhs.net

Leicestershire Partnership NHS Trust

Principal Investigator: Dr. Fabida Noushad Fabida.Noushad@leicspart.nhs.uk

Principal contact: Dave Clarke dave.clarke@leicspart.nhs.uk

Lincolnshire Partnership NHS Foundation Trust

Principal Investigator: Christine Coupar Christine.coupar@lpft.nhs.uk

Principal contact: Tracy McCranor Tracy.McCranor@lpft.nhs.uk

North East London NHS Foundation Trust

Principal Investigator: Eilis Quinlan Eilis.Quinlan@nelft.nhs.uk

Principal contact: Ana Cardoso Ana.Cardoso@nelft.nhs.uk

Oxford Health NHS Foundation Trust

Principal Investigator: Dr. Pamela Kaushal Pamela.Kaushal@oxfordhealth.nhs.uk

Sub Principal Investigator and principal contact: Taneesha Jones-Seale Taneesha.JonesSeale@oxfordhealth.nhs.uk

Somerset Partnership NHS Foundation Trust

Principal Investigator and principal contact: Carinna Vickers Carinna.Vickers@sompar.nhs.uk

South London and Maudsley NHS Foundation Trust

Principal Investigator:  Henrietta Webb-Wilson Henrietta.Webb-Wilson@slam.nhs.uk 

Principal contact: Carol Cooley carol.cooley@kcl.ac.uk

Sussex Partnership NHS Foundation Trust

Principal Investigator: Dr. Mark Hayward M.I.Hayward@sussex.ac.uk

Principal contact: Kelly Wilson Kelly.Wilson@sussexpartnership.nhs.uk