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. 2020 Jul 20;12:64. doi: 10.1186/s13073-020-00759-w

Table 2.

Results of eQTL and meQTL mapping using Matrix eQTL and coQTL discovery by GWAS. Numbers in parentheses for eQTLs and meQTLs refer to the number of unique genes (genes whose expression levels are associated with the QTL) and meCpGs (CpG sites whose methylation levels are associated with the QTL), respectively

Category Threshold Vehicle IL-13 IL-17A IL-13+IL-17A
eQTLs FDR = 5% 2595 (140) 3262 (161) 2524 (133) 2765 (139)
meQTLs FDR = 5% 10,797 (1718) 9859 (1515) 11,274 (1710) 13,222 (2046)
coQTLs P < 0.01 9087 8705 9776 9370

Sex, age, imputed smoking, and the first two ancestry PCs were included as covariates