Figure 3.

Cortical mitochondria provide a regional source of energy. Possible mechanisms by which mitochondria accumulation on the cortical cytoskeleton enhance tumor cell motility and invasion. When mitochondria reach the leading edge of the cell, local production of ATP and GTP by mitochondrial bioenergetics enable energy‐expensive cellular processes. Examples of the consumption of ATP and GTP for signal transduction and energy‐dependent molecular, cellular, and structural homeostasis in cells are provided