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. 2019 Nov 20;245(4):330–341. doi: 10.1177/1535370219889323

Figure 2.

Figure 2.

PAI-guided drug delivery. (a) PAI of three replicates of plastic tubing holding blood with increasing concentrations of heparin along with same concentration of methylene blue. Reprinted (adapted) with permission from Wang J, Chen F, Arconada-Alvarez SJ, Hartanto J, Yap LP, Park R, Wang F, Vorobyova I, Dagliyan G, Conti PS, Jokerst JV, A nanoscale tool for photoacoustic-based measurements of clotting time and therapeutic drug monitoring of heparin. Nano Lett 2016;16:6265–71. Copyright © 2016 American Chemical Society. (b) Photoacoustic tomography of injection boundary of lithium-based sensors into mice. Reprinted (adapted) with permission from Cash KJ, Li C, Xia J, Wang LV, and Clark HA, Optical Drug Monitoring: Photoacoustic Imaging of Nanosensors to Monitor Therapeutic Lithium in Vivo. ACS Nano 2015;9:1692–98. Copyright © 2015 American Chemical Society. (A color version of this figure is available in the online journal.)