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. 2019 Jan 7;40(2):392–403. doi: 10.1177/0271678X18822474

Figure 4.

Figure 4.

PS1, a major γ-secretase component, was significantly increased in microvascular tissue of eNOS+/− mice. (a) Microvascular tissue from 18-month-old eNOS+/− and wild type animals was analyzed by Western blot analyses for γ-secretase components: PS1, PS2, nicastrin, Pen2, and Aph1. Representative image is shown. Densitometric analysis was performed for (b) PS1 (n = 6 animals; *P < 0.05), (c) PS2 (n = 4 animals), (d) nicastrin (n = 6 animals), (e) Pen2 (n = 6 animals), and (f) Aph1 (n = 4 animals). All data are presented as mean±SD with individual data points shown.