Figure 4.

tMCAo does not induce meningeal lymphangiogenesis. (a) Infarct volumes in mice that received a transient middle cerebral artery occlusion (tMCAo; green circles; n = 7) compared to uninjured sham mice (black circles; n = 5). Inset shows representative cresyl violet-stained cortical section with infarct highlighted in red (b) Representative image of LVs at the sagittal sinus (ss). (c) Quantification of meningeal lymphatic vessels at the sagittal sinus (p = 0.11) and (d) to the right of the sagittal sinus (p > 0.99) two weeks after tMCAo (n = 5) or after sham surgery (n = 5). All data presented as mean ± SD and were analyzed using a Mann–Whitney test. **p < 0.01. Scale ba = 200 µm.