Table 3.
Overall and entity-specific survival analysis
| N | Kaplan–Meier model | Univariate Cox regression | Multivariate Cox regression | |||
|---|---|---|---|---|---|---|
| Median EFS | p | HR | p | |||
| Overall | ||||||
| LAG3 score | ||||||
| <1% TILs | 69 | |||||
| 1–4% TILs | 14 | 116 | 0.350 | 1.64 | 0.327 | |
| ≥ 5% TILs | 14 | 38 | 0.400 | 1.43 | 0.477 | |
| LAG3 status | ||||||
| Negative | 69 | |||||
| Positive | 28 | 116 | 0.275 | 1.53 | 0.279 | |
| TP53 type | ||||||
| Wild type | 64 | 116 | ||||
| Null type | 12 | 18 | 0.014 | 3.20 | 0.015 | p = 0.065 |
| Overexpression | 18 | 96 | 0.962 | 1.02 | 0.967 | |
| Adenoid cystic carcinoma | ||||||
| LAG3 score | ||||||
| < 1% TILs | 20 | 67 | ||||
| 1–4% TILs | 4 | 12 | 0.004 | 6.85 | 0.011 | |
| ≥ 5% TILs | 2 | 17 | 0.702 | 1.50 | 0.704 | |
| LAG3 status | ||||||
| Negative | 20 | 67 | ||||
| Positive | 6 | 17 | 0.039 | 3.46 | 0.053 | p = 0.091 |
| TP53 type | ||||||
| Wild type | 18 | 67 | ||||
| Null type | 2 | 9 | 0.001 | 25.76 | 0.010 | |
| Overexpression | 4 | 27 | 0.818 | 1.20 | 0.824 | |
Significant p values are printed in bold type. For multivariate regression, only p value below 0.1 are displayed