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. 2020 Jul 9;33(6):435–454. doi: 10.1089/ars.2020.8046

FIG. 3.

FIG. 3.

Landscape of NOX protein expression in human cancer specimens from TCGA. Hierarchical clustering on log-transformed mean gene expression values in 32 cohorts of TCGA (TCGA Research Network). Columns were clustered by using Euclidian distance and complex linkage. mRNA expression data (batch-normalized read counts from Illumina HiSeq_RNASeqV2) was downloaded from cBioPortal (72). Red: higher expression; white: lower expression; gray: missing value. The number of specimens per cohort is indicated in parentheses. ACC, adrenocortical carcinoma; AML, acute myeloid leukemia; BLCA, bladder urothelial carcinoma; BRCA, breast invasive carcinoma; CESC, cervical squamous cell carcinoma; CHOL, cholangiocarcinoma; COADREAD, colorectal adenocarcinoma; DLBC, diffuse large B cell lymphoma; ESCA, esophageal adenocarcinoma; GBM, glioblastoma multiforme; HNSC, head and neck squamous cell carcinoma; KICH, choromophobe renal cell carcinoma; KIRC, renal clear cell carcinoma; KIRP, renal papillary cell carcinoma; LGG, brain lower grade glioma; LIHC, liver hepatocellular carcinoma; LUAD, lung adenocarcinoma; LUSC, lung squamous cell carcinoma; MESO, mesothelioma; mRNA, messenger RNA; OV, ovarian serous cystadenocarcinoma; PAAD, pancreatic adenocarcinoma; PCPG, pheochromocytoma and paraganglioma; PRAD, prostate adenocarcinoma; SARC, sarcoma; SKCM, skin cutaneous melanoma; STAD, stomach adenocarcinoma; TCGA, The Cancer Genome Atlas; TGCT, testicular germ cell tumors; THCA, thyroid carcinoma; THYM, thymoma; UCEC, uterine corpus endometrial carcinoma; UCS, uterine carcinosarcoma; UVM, uveal melanoma.