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. 2018 Jan 26;2(1):NS20170181. doi: 10.1042/NS20170181

Figure 4. Smad1 and Smad5 are important for neurite growth induced by miR-181a inhibition.

Figure 4

(A) Neurite length and (B) neurite branching of SH-SY5Y cells transfected with control siRNA or Smad1 siRNA or Smad5 siRNA and a GFP-expressing plasmid together with a control or miR-181a antagomir for 72 h (*P<0.05, ***P<0.001 compared with control) (#P<0.05, ##P<0.01, ###P<0.001 ANOVA with post-hoc Tukey’s test; 40 cells for each group per experiment; n=3 experiments). All data are presented as mean ± S.E.M. (C) Representative photomicrographs of GFP+ neurons in cultures of E14 rat VM. Scale bar as indicated.