Table 1. GO categories and KEGG pathways represented in the list of hsa-miR-181a predicted target genes relative to the background gene population.
ID | Category name | Observed genes | Expected genes | Enrichment ratio | Adjusted P value |
---|---|---|---|---|---|
GO term | |||||
GO:0007399 | Nervous system development | 161 | 90.27 | 1.78 | 1.46 × 10−10 |
GO:0043005 | Neuron projection | 60 | 31.57 | 1.90 | 8.39 × 10−05 |
KEGG | |||||
04722 | Neurotrophin signalling pathway | 18 | 2.59 | 6.94 | 1.82 × 10−08 |
04350 | TGF-β signaling pathway | 10 | 1.72 | 5.83 | 5.36 × 10−05 |
04010 | MAPK signalling pathway | 24 | 5.47 | 4.38 | 5.48 × 10−08 |
04310 | Wnt signalling pathway | 13 | 3.06 | 4.24 | 7.64 × 10−05 |