Table 1. NPC regulation of CNS vascularisation.

Process	NPC signal/molecule	Species/CNS region	References
(1) Vascular ingression and intraneural branching	VEGF-A	Fish spinal cord	[15]
		Mouse forebrain	[16,17]
		Mouse mid-/hindbrain	[17]
	WNT7A/7B	Mouse spinal cord	[18,19]
(2) Branching/angiogenesis	VEGF-A	Fish spinal cord	[15]
		Mouse forebrain	[16,17]
		Mouse mid-/hindbrain	[17]
(3) Vessel maturation/BBB formation	WNT7A/7B	Mouse spinal cord	[18,19]
(4) Vascular stability (via TGFβ activation)	Integrins αvβ6 and αvβ8	Mouse forebrain	[20,21]